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American Academy of Ophthalmology

American Academy of Ophthalmology

Understanding Ischemic Optic Neuropathy

Understanding Ischemic Optic Neuropathy

Ischemic optic neuropathy can cause sudden loss of vision. Learn about the risks, signs, symptoms, and what can be done to minimize damage.


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Ischemic optic neuropathy (ION) is a sudden and often irreversible condition in which the optic nerve—responsible for transmitting visual information from the eyes to the brain—suffers damage due to reduced blood flow. Without sufficient oxygen and nutrients, the nerve ceases to function properly, leading to permanent vision loss in one or both eyes. While total blindness is rare, most affected individuals experience substantial visual impairment that cannot be reversed.

Recognizing Symptoms and Understanding Risk

The earliest sign of ION may be a transient ischemic attack (TIA) or mini-stroke—brief episodes of dimmed vision lasting seconds or minutes. These temporary disruptions serve as critical warnings and require immediate medical evaluation to prevent full-scale vision loss. Once ION sets in, it can affect central vision, peripheral vision, or both. Since the optic nerve cannot regenerate, any resulting damage is typically permanent.

Several health conditions increase the risk of developing ION, including:

  • High blood pressure 
  • High cholesterol 
  • Diabetes
  • Heart disease 
  • Glaucoma 
  • Sleep apnea 

Temporal arteritis—a serious inflammation of the head arteries—can also trigger ION and may lead to severe, bilateral vision loss if not treated quickly. People over the age of 50 face a significantly higher risk.

Diagnosis, Treatment, and Management Options

Diagnosis involves a comprehensive eye exam, including:

  • Dilation to assess the optic nerve, 
  • Peripheral vision testing, and 
  • Blood tests to detect inflammation.

 If ION is linked to temporal arteritis, immediate treatment with corticosteroids may protect the unaffected eye.

Although no treatment can restore lost vision, managing underlying conditions like hypertension or diabetes may help prevent further damage. Patients are often referred to low vision specialists who can provide magnifiers, assistive devices, and strategies for adapting to visual limitations, helping them maintain independence and quality of life.

*Gregori, N. Z. (2024, September 16). What Is Ischemic Optic Neuropathy? American Academy of Ophthalmology. https://www.aao.org/eye-health/diseases/what-is-ischemic-optic-neuropathy 

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