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National Institute on Aging

National Institute on Aging

The Importance of Clinical Research for Glaucoma

The Importance of Clinical Research for Glaucoma

Learn what clinical trials are, what they involve, and why they’re essential for people living with glaucoma.


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Clinical research is fundamental to medical advancements and has led to the development of numerous treatments that save lives and improve the quality of life for people around the world. 

It helps find techniques for diagnosing diseases earlier, enhance preventative strategies, design safer and more effective treatments, and improve patient care for better outcomes. 

By participating in clinical research, individuals can contribute to these advancements. The participation of diverse groups of people is essential in order to generalize the findings and ensure that new treatments are effective across different populations and conditions. Learn more about the importance of participating in clinical research for glaucoma.*

Benefits of Clinical Trials for Glaucoma

Glaucoma is one of the primary causes of blindness worldwide, and it’s both irreversible and preventable. Clinical trials are responsible for the ever-improving range of treatments available for managing the condition and avoiding further vision loss, particularly if detected and treated in its early stages.

In addition to medicated eye drops, which remain many ophthalmologists’ first line of treatment, clinical research has also provided patients with such options as:

  • Injections,
  • Laser therapy,
  • Minimally-invasive implantation of a shunt, and
  • Minimally-invasive implantation of a long-term drug delivery device.

The U.S. spends billions of dollars each year to prevent blindness in people with or at risk for developing glaucoma.

What Is Clinical Research?

Clinical research encompasses two primary types of studies: observational studies and clinical trials. Observational studies involve monitoring people in their everyday settings, to collect and compare data over time, without intervening or altering participants’ regular routines. 

In contrast, clinical trials are more direct interventions that test the safety and efficacy of new:

  • Treatments such as drugs, surgeries, or therapeutic devices, and 
  • Diagnostic tools and techniques.

Clinical trials are vital for determining whether a new treatment is an improvement over existing solutions regarding:

  • How well different doses address specific disease symptoms over time, 
  • What kinds of side effects does the treatment cause, and
  • Whether or not the benefits of the treatment outweigh the risks.

The Processes Involved in Clinical Research

The methodology of clinical research is rigorous and structured to ensure safety and reliability. Participants in clinical trials undergo a detailed informed consent process, ensuring they understand the implications and procedures involved. 

Screening processes then assess whether they qualify for the study based on specific inclusion and exclusion criteria. Throughout the trial, participants are closely monitored through regular visits and assessments to ensure their well-being and to gather valuable data.

Clinical research plays a pivotal role in the advancement of medical science, offering hope and new possibilities for better health outcomes worldwide. Through the diligent and ethical conduct of studies, researchers continue to make significant strides in understanding and treating complex health issues.

*National Institute on Aging. (2023, March 22). What Are Clinical Trials and Studies? Retrieved from https://www.nia.nih.gov/health/clinical-trials-and-studies/what-are-clinical-trials-and-studies#:~

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