Glaucoma remains a leading cause of vision loss worldwide, and while a definitive cure is still out of reach, significant advancements have been made over the past few years. Innovations in sustained-release drug delivery systems, medical devices, and research initiatives are shaping the future of glaucoma management. Here is a brief overview of the most notable innovations in glaucoma treatment and research.*

Breakthroughs in Glaucoma Treatments

Improved Drug Delivery Systems 

One of the major challenges in glaucoma treatment is medication adherence, with nearly half of patients failing to take their prescribed eyedrops consistently. To address this issue, two innovative sustained-release drug delivery systems have been introduced:

• Durysta®. This biodegradable implant gradually dissolves over about six months. It releases a prostaglandin analog that enhances fluid drainage from the eye, helping to lower intraocular (internal eye) pressure.
• iDose® TR. This implant delivers travoprost directly into the eye for up to three years.

Advancements in Laser Procedures

Selective laser trabeculoplasty (SLT) has gained traction as a primary treatment option for glaucoma, reducing IOP by stimulating your eye’s natural drainage system. A significant innovation in this field is:

• Belkin Vision’s “Eagle” Device. The first no-contact laser system for SLT, Eagle ensures precision with an automated targeting system and an eye-tracking feature to compensate for eye movement. 

Research Developments

Research efforts continue to explore novel approaches for glaucoma diagnosis and treatment. Noteworthy areas of progress include:

• Gene and stem cell therapies. Scientists are investigating the potential of gene therapies and stem cell treatments to regenerate and transplant optic nerve cells, offering hope for patients with retinal degenerative diseases.
• Artificial Intelligence (AI) in diagnosis. AI algorithms are being developed to enhance early detection and diagnosis of glaucoma, potentially enabling timely intervention and better management of the disease.
• Genetic risk factors. Research is underway to identify additional genes associated with an increased risk of glaucoma, paving the way for more personalized treatment approaches.

These advancements reflect a concerted effort to improve glaucoma care, offering patients and clinicians new tools to manage this complex disease more effectively.

*Harmon, G. (2025, January 15). Doctor, I Have a Question. What Are Some Recent Advances in the Treatment of Glaucoma? The Glaucoma Foundation Newsletter. https://glaucomafoundation.org/doctor-i-have-a-question-what-are-some-recent-advances-in-the-treatment-of-glaucoma/